Diego factor has not been found in pure Caucasians and known to be present
exclusively among American Indians and Mongolians. Regarding Mongolian bloods
Layrisse and Arends tested 100 Chinese bloods dwelling in Venezuela against
fanti-Diα and found 5 positives. They tested 65 Japanese bloods in the
same area and found 8 positives or a positivity of 12.31%. Ever since, the frequencies of
Diego factor in Japanese have been studied by Lewis and many other Japanese workers
and a high incidence is well recognized.
Regarding the incidence of Diego factor among Korean bloods, there is only one report
by Won et al. This work was carried out in America transporting the blood samples
fan, Seoul to Minnesota. For the first time in Korea the author studied with
anti-Diα serum supplied by the Knickerbocker Laboratory under the
auspieces of the China Medical Board. Employing an indirect Coombs technique 117
random Korean bloods were tested and found 17 positive ones or a positivity of 14.5%.
The calculated gene frequency of Diα+gene is 0.0755 and of Diα
-gene is 0.9245. As shown in Table 1 Won's data on Koreans was 6.14% and
the incidencies among Japanese vary from 3.2% to 12.3%. Our data is slightly higher
than these and whether this has any statistical significance is in doubt but at least this
proves that Korean has Diego factor not less frequently than Japanese. It was our
experience that the agglutination with anti-Diα was very weak, at most
one plus rending, and the wide discrepancies among same race would be mainly due to
the different technique and different strength of antiserum.
Anti-Luα and anti-Lub sera were supplied by Dr.
Greenwalt of Milwaukee Blood Center and 95 samples were tested with
anti-Lub and 20 were tested with anti-Lub. Both positive
and negative control cells were tested together. As shown in Table 2 the samples were
all negative for anti-Luα and all positive for anti-Lub.
Sanger, Walsh and Kay hate reported the same pattern among Australian aborigines and
New Guinea natives. Anthropological studios on other Asiatic rams are limitted.
Caucasians, Negroes and American Indians show relatively high incidencies.
Anti-Leα was also obtained from Dr. Greenwalt. No
anti-Leb was available. Among 75 Korean bloods there were 22 Le(a+)
bloods. The osculated positivity would be 29.3%. This is a little higher incidence than
other reported data on Monglian bloods but if one combines this data with other two
series on Chinese bloods listed in Table 3, the over all positivity of Mongolian bloods
would become about 23%, which is the average Positivity of whites and Negroes.
Anti-P was supplied from the Knickerbocker Laboratory and 106 samples were tested.
The postivity was 52.8% and the calculated gene frequency of P was 0.3132 and of
P-was 0.6868.
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